Surgo study of TB patients in India published in BMJ Global Health suggests making it more convenient to seek care for TB more effective than awareness-raising

Tuberculosis (TB) is a leading cause of death worldwide, with India having the largest number of people with TB and a significant number who put off seeking care for TB-related symptoms. While previous research suggested that lack of awareness about TB is a key factor in delaying care seeking, a study of TB patients in the south Indian city of Chennai by Surgo Foundation found otherwise, and identified a key subpopulation for targeting pro-care seeking messages.  

The first-of-its-kind study, conducted by Surgo Foundation in partnership with the Clinton Health Access Initiative and the Greater Chennai Corporation in 2018-19 and published in the latest edition of BMJ Global Health, found that TB awareness is widespread, and not associated with care-seeking delays--suggesting that intervention efforts should focus less on awareness campaigns and more on making it easier to visit a doctor. 

Surgo researchers identified multiple barriers to prompt care-seeking, including: 

  • demographic factors such as occupation (lack of time, rather than money, was a significant barrier to care-seeking)

  • beliefs around perceived risk (higher risk perception → care-seeking)

  • normalization of TB (lower care-seeking) 

  • symptom-related factors, such as sustained weight loss or having a fever for at least 7 days (higher care-seeking)

Surgo identified distinct segments of the population to better understand TB-symptomatic people in Chennai who do not promptly seek care. This process revealed a key subpopulation: employed men who problem-drink and smoke, comprising just over half -- 54% -- of this population. Surgo is currently working with its partners to design and deploy new interventions that reach this target population. 

“This work sums up the kind of impact we strive for: Designing a precision approach to a significant public health problem, and developing targeted interventions for key population segments,” said Sema Sgaier, executive director of Surgo Foundation. “In this case, we’ve made significant strides to address India’s struggle with TB by identifying a subpopulation -- employed men -- that seeks care for TB at the lowest rates, while comprising 64% of the risk. We learned that we need to make care seeking as convenient as possible for this group, while also increasing their perceptions of the risks of not getting treated.”

Read Surgo’s paper, “Understanding why at-risk population segments do not seek care for tuberculosis: a precision public health approach in South India,” in the September 2020 edition of BMJ Global Health

Original Surgo research on maternal health published in BMJ Global Health

The quality of care a patient receives when giving birth is influenced substantially more by the facility in which she receives care than by the provider who provides the care, according to original research conducted by Surgo Foundation and published in the latest edition of BMJ Global Health.

“Our research has important implications for efforts to reduce maternal and infant mortality in low- and middle income countries,” said Dr. Sema Sgaier, executive director of Surgo Foundation and Adjunct Assistant Professor at the Harvard T.H. Chan School of Public Health. “It suggests that instead of designing interventions that focus primarily on shifting the behavior of healthcare providers, we should design interventions that focus on the culture and characteristics of the facility as a whole.”

Considering that half of all maternal deaths and one million newborn deaths each year are due to poor quality healthcare, scientists from Surgo Foundation set out to explore how much of an influence care providers, medical facilities, and countries have on pregnant women’s quality of care during labor and delivery.

The team looked at a set of vital signs-related data gathered from women arriving at facilities to deliver a baby in Uttar Pradesh, India. They compared this data with observations of labor and delivery visits in facilities in Kenya and Malawi, including the labor and delivery itself, and care during the immediate postpartum period. Their key finding: not only is the quality of care a patient receives influenced more by facility than health care provider, but this is true even for aspects of care that do not require specialized training or equipment.

Read Surgo’s paper, “Facilities are substantially more influential than care providers in the quality of delivery care received: A variance decomposition and clustering analysis in Kenya, Malawi and India,” in the August 2020 edition of BMJ Global Health.

Surgo launches new Africa COVID-19 Community Vulnerability Index

NOTE: Updated July 23, 2020

Today Surgo Foundation unveiled the Africa COVID-19 Community Vulnerability Index (Africa CCVI), a tool designed to fill a critical information gap and help African governments, health officials, non-governmental organizations, and others respond to the coronavirus pandemic. It  finds that although Africa has not yet been overwhelmed by COVID-19, several regions are showing troubling signs of vulnerability to the social, economic, and health impacts of an outbreak that should not be ignored. 

The Africa CCVI was modeled after Surgo’s U.S. COVID-19 Community Vulnerability Index, which is featured as a resource by the U.S. Centers for Disease Control and Prevention. It is the first Pan-African index  to assess vulnerability to COVID-19 not just across, but within countries, at a granular level.

“By showing us the different ways African regions can be vulnerable to COVID-19 beyond just mortality, this index gives us predictive power we’ve never had before,” said Dr. Sema Sgaier, executive director of Surgo Foundation. “While it does not predict which regions are at risk of having outbreaks, it does predict whether that region is able to mitigate the health, economic, and social impacts of COVID-19 and what downstream consequences they should plan for.”

The Africa CCVI ranks 751 regions across 48 African countries in terms of vulnerability to COVID-19 based on seven key themes: socioeconomic status, population density, access to transportation and housing, epidemiological factors, health system factors, fragility, and age of population. It is the only index to measure vulnerability to COVID-19 across the African continent at a subnational level. 

The Africa CCVI is made possible in part by a generous #COVIDaction Data Challenge award from the Department for International Development (DFID)’s Frontier Technologies Hub

Underscoring the importance of DFID’s first investment in the COVIDaction Data Challenge, James Duddridge, the UK’s Minister for Africa, noted, “The extent of the impact of coronavirus in Africa is still unclear. Governments, NGOs and health workers need access to the right information so they can tackle the virus where there is a risk of it spreading and help save lives. We have so far committed £764 million of UK aid to help poorer countries tackle coronavirus, including through supporting innovative uses of data. It is only through global cooperation that we can end this pandemic and keep the whole world safe.” 

“The Africa COVID-19 Community Vulnerability Index will empower us with the data we need to stay ahead of the virus,” said Solomon Zewdu, deputy director for Ethiopia, Global Development, and COVID-19 coordinator for Africa at the Bill and Melinda Gates Foundation. “It enables us to design targeted interventions and deploy resources exactly where they are needed, armed with a better understanding of how and why specific African regions are particularly vulnerable to COVID-19.”  

Key Findings

1. Africa’s relatively young population is so far proving to be its best defense against COVID-19 deaths

  • Regions with low age-related vulnerability--Nairobi in Kenya, or Federal Capital Territory (Abuja) in Nigeria--will fare better in terms of COVID-19 hospitalizations, people needing critical care, and fatality rates.

  • Limited health systems in poor African countries like Mozambique and Mali are in part offset by their younger populations, which have several times lower projected hospitalization rates compared to rich countries like South Africa and Egypt. These wealthier countries in North and South Africa have older populations, which are far more vulnerable to hospitalizations and poor COVID-19 outcomes. 

  • The average projected infection fatality rate (IFR) for Africa, based on the age and gender distribution, health system quality, and co-morbidities, is 0.55%; for most regions the IFR ranges between 0.22% and 0.76%, which is 2 to 6 times lower than the IFR for the US (1.3%). However, we do see a few outliers with IFR above 1% - e.g. northern Tunisia - because of its relatively older population. 

2. Vulnerability to COVID-19 is not distributed evenly across the continent, with drivers of vulnerability varying by region.

  • The Top 10 most vulnerable regions across Africa are found across three countries: Democratic Republic of Congo (with eight of the most vulnerable regions), Chad, and Mali.

  • Some countries have similar levels of vulnerability, but for different reasons. For example, in South Africa there is widespread vulnerability due to epidemiological risk factors and fragility, but the primary driver of vulnerability in Chad is socioeconomic factors, while the primary driver of vulnerability in Cameroon is fragility.

  • There are many regions with similar levels of vulnerability within a country, like Sahel and Sud-Ouest in Burkina Faso, where different underlying reasons account for that vulnerability. Sahel’s vulnerability derives from its position as the epicenter of humanitarian violence in the country, while Sud-Ouest contains the greatest percentage of Burkina Faso’s elderly population.

3. Many kinds of vulnerability co-exist within regions, and seem to be correlated to some extent:

  • Many regions that experience vulnerability due to socioeconomic factors are also experiencing vulnerability due to the strength of their health systems and the quality of their housing. This is the case in the Somali region of Ethiopia, Tahoua region of Niger, and Manyara region of Tanzania.

  • Regions with high socioeconomic vulnerability tend to have low vulnerability in terms of population density and epidemiological factors, as is the case with the Thaba-Tseka region of Lesotho or the Alibori region of Benin.

  • High epidemiological vulnerability tends to mean low vulnerability due to age, as is the case in the Abidjan region of Côte d'Ivoire or the Lilongwe region of Malawi, where many people die before reaching old age.

4. Mobility has by and large decreased across the continent over the last few months, but the most vulnerable areas are the least likely to practice social distancing.

  • Across 16 countries in Africa with available mobility data, there was an overall reduction in mobility of ~12.2% since mid-February relative to pre-COVID-19 movement, which is encouraging for virus control. 

  • People in more vulnerable regions such as Yobe, Zamfara, and Bauchi, Nigeria have not been social distancing as much as their counterparts in less vulnerable regions such as Lagos, Federal Capital Territory, and Osun, Nigeria--which increases their probability for infection and compounds those regions’ challenges in fending off the virus.

  • On average, the more vulnerable a region is due to health system factors, the less social distancing they are doing (even though poor health systems especially need a “flattening of the curve” through social distancing).  This is the case in regions like Al Wadi al Jadid, Egypt, Kavango, Namibia, and Mara, Tanzania.

  • On average, the more vulnerable an area is due to population density and epidemiological factors, the more social distancing they are doing--as is the case in regions like Dakar, Senegal and Western Cape, South Africa.

“The Africa CCVI can tell users what areas are vulnerable and why, helping inform more precise, effective responses,” said Sgaier. “For example, if a region is vulnerable due to high population density, responses could include a significant scale up of social distancing measures. Or if a region is vulnerable due to spotty health system infrastructure, responses could include ramping up mobile health services.” 

“The Africa COVID-19 Community Vulnerability Index fills an information gap that has challenged the global development community for too long,” said Magdalena Banasiak, a Senior Innovation Adviser at DFID that manages the COVIDaction program. “Until now, limited COVID-19 data in Africa has not provided a true reflection of where this pandemic could have the greatest impact--partly due to low scale-up of testing, and partly due to incomplete reporting. Now we can understand how to prioritize pandemic response efforts not just across, but within African countries."

To explore the index and learn more, visit precisionforcovid.org/africa.

 

Technical Notes:

Countries excluded due to lack of data: Cape Verde, Equatorial Guinea, Guinea-Bissau, Mauritius, Mayotte (France), Réunion (France), São Tomé and Príncipe, Seychelles, and Western Sahara.

Data Sources: Demographic and Health (DHS) Surveys, Institutes of Health Metric and Evaluation (IHME), Malaria Atlas Project, Uppsala Conflict Data Program, UNHCR, World Bank, Open data for Africa, Multiple Indicator Cluster Surveys (MICS), Armed Conflict Location & Event Data Project (ACLED), Global Roads Inventory Project, World Pop, and Global Data Lab. Mobility data are from Google. Fatality and hospitalization rates are from Salje et al. (2020) in Science and kindly provided by Dr Mumtaz and Prof. Raddad. 

About Surgo Foundation

Surgo Foundation, based in Washington, D.C., is a nonprofit organization dedicated to solving health and social problems with precision.  We do this by bringing together all the tools available from behavioral science, data science, and artificial intelligence to unlock solutions that will improve and save lives. We work in the United States and in low-income countries on issues like COVID-19, HIV/AIDS, tuberculosis, maternal mortality, health care, housing, and more. Visit us at surgofoundation.org.

About COVIDaction

COVIDaction is a partnership between DFID’s Frontier Technology Hub, Global Disability Innovation Hub (GDI Hub), and UCL’s Institute of Healthcare Engineering along with other collaborators, designed to explore these questions. The partnership is working with a range of partners to build a technology and innovation pipeline to support action related to the COVID-19 pandemic across key thematic areas. Together we plan to scan the globe for promising ideas, evaluate and make sense of what we find, support the very best ideas with grant funding and venture support and share what we learn along the way. The partnership seeks to support ideas across data, local production and solutions, and resilient health systems. Find out more at medium.com/covidaction.  

Contact: Bethany Hardy at Surgo Foundation at bethanyhardy@surgofoundation.org or (202) 277-3848.